Reprints Available Upon Request

In prep/In press/Submitted

Albertini RJ, Carson ML, Kirman CR, Gargas ML.  2009.  Mutagenicity of 1,3-butadiene's Major Metabolites:  Relevance for Carcinogenic Potency.   Crit Rev Toxicol (In prep).

Aylward, L.L, M.K. Morgan, T.E. Arbuckle, D.B. Barr, C.J. Burns, B.H. Alexander, S.M. Hays.  In press.  Biomonitoring data for 2,4-dichlorophenoxyacetic acid in the US and Canada:  Interpretation in a public health risk assessment context using Biomonitoring Equivalents.  Environ. Health Perspect.

Aylward, L.L., K.M. Bodner, J.J Collins,. M. Wilken, D. McBride, C.J. Burns, S.M. Hays, N. Humphry.  In press.  TCDD exposure estimation for workers at a New Zealand 2,4,5-T manufacturing facility based on serum sampling data.  J. Exp. Sci. Environ. Epidem.

Aylward, L.L., S.M. Hays, M. Gagné, K. Krishnan.  In press.  Derivation of Biomonitoring Equivalents for di(2-ethylhexyl)phthalate (CAS No. 117-81-7). Regul. Toxicol. Pharmacol.

Aylward, L.L., S.M. Hays, M. Gagné, K. Krishnan.  In press.  Derivation of Biomonitoring Equivalents for di-n-butyl phthalate (DBP), benzylbutyl phthalate (BzBP), and diethyl phthalate (DEP).  Regul. Toxicol. Pharmacol.

Buchanan, S., Elliott, G. Toner, T., Pyatt, D. and Carpenter, J. 2009 "Mechanistic Study on Loss of Clonogenic Potential of a Lyophilized CD34+ Cell Line during Processing and Following Ambient Storage" Submitted PloS Biology.

Buchanan, S., Pyatt, D.W. and Carpenter, J. 2009 "Preservation of Differentiation and Clonogenic Potential of Lyophilized Human Hematopoietic Stem and Progenitor Cells Loaded with Trehalose following Ambient Storage" Submitted PloS Biology.

Collins, J.J., K. Bodner, L.L. Aylward, M. Wilken, G. Swaen, R. Budinsky, C. Rowlands, C.M. Bodnar.  In press.  Mortality rates among workers exposed to dioxins in the manufacture of pentachlorophenol.  J. Occ. Env. Med.

Garabrant, D.H., L.L. Aylward, S. Berent, Q. Chen, C. Timchalk, C.J. Burns, S.M. Hays, and J.W. Albers.  In press.  Cholinesterase inhibition in chlorpyrifos workers: Characterization of biomarkers of exposure and response in relation to urinary TCPy.  J. Exp. Sci. Environ. Epidemiol.

Hays, S.M., L.L. Aylward, M. Gagné, K. Krishnan.  In press.  Derivation of Biomonitoring Equivalents for cyfluthrin.  Regul. Toxicol. Pharmacol.

Kirman CR, Albertini RA, Gargas ML.  2009.  Assessing the Carcinogenic Modes of Action for 1,3-Butadiene. Crit Rev Toxicol (In prep).

Kirman CR, Albertini RJ, Sweeney LM, Gargas ML.  2009.  The Metabolism of 1,3-Butadiene and its Implications to Human Health Risk Assessment.  Crit Rev Toxicol (In prep).

Kirman CR, Budinsky RA, Yost L, Baker BF, Zabik JM, Rowlands JC, Long TF, Simon T.  2009.  Derivation of Soil Cleanup Levels for 2,3,7,8-Tetrachloro- dibenzo-p-dioxin (TCDD) Toxic Equivalence (TEQD/F) in Soil through Deterministic and Probabilistic Risk Assessment of Exposure and Toxicity.  (In prep)

Kirman CR, Yost L, Hoelm, RR , Sorensen MT, Aylward, LL, Hubner RP, Landenberger B, Budinsky RA, Zabik J, Price PS.  2009. Evaluation of Exposure to PCDD/Fs Toxic Equivalence (TEQD/F) from Consumption of Fish Harvested from Tittabawassee and Saginaw Rivers Based on Site-Specific Fishing Data and Recent Residue Measurements.  (In prep)

LaKind, J.S., D.Q. Naiman, S.M. Hays, L.L. Aylward, B.C. Blount.  In press.  Public health interpretation of trihalomethane blood levels in the United States:  NHANES 1999-2004.  J. Exp. Sci. Environ. Epidem.

McBride, D.I., J.J. Collins, N.F. Humphry, P. Herbison, K.M. Bodner, L.L. Aylward, C.J. Burns, M. Wilken.  In press.  Mortality in Workers Exposed to 2,3,7,8-Tetrachlorodibenzo-p-dioxin at a Trichlorophenol Plant in New Zealand.  J. Occ. Env. Med.

Pyatt, D., Hays, S., and Aylward, L. 2010 "Benzene and Childhood Leukemia" Submitted to Chemico-Biological Interactions.

Simon, T., L. Aylward, C.R. Kirman, C. Rowlands, R. Budinsky.  In press.  Estimates of cancer potency of 2,3,7,8-tetrachlorodibenzo-p-dioxin using linear and non-linear dose-response modeling and toxicokinetics.  Toxicol. Sci.

Sweeney, L.M., C.R. Kirman, M.L. Gargas, and R.G. Tardiff. 2009.  Development of a physiologically-based toxicokinetic model of acrylamide and glycidamide in rats and humans and its application to the estimation of safe dietary exposures."  In preparation for submission to J Food and Chemical Toxicology 

Tardiff, R.G., Bevan, C., Carson, M.L., Sweeney, L.M., Kirman, C.R., Tan, Y., Andersen, M. And Gargas, M.L. 2009. Derivation of a drinking water equivalent concentration and maximum contaminant level goal (MCLG) for perfluorooctanoic acid (PFOA), a persistent water soluble compound. Fd. Chem. Toxicol., in preparation.

 

Published

Collins, J.J., K. Bodner, L.L. Aylward, M. Wilken, C.M. Bodnar. 2009.  Mortality rates among trichlorophenol workers with exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Am J Epidemiol. 170(4):501-6.

Gargas ML, Kirman CR, Sweeney LM, Tardiff RG.  2009.  Acrylamide: Consideration of species differences and nonlinear processes in estimating risk and safety for human ingestion.  2009.   Food Chem Toxicol. Apr;47(4):760-8.

Hays, S.M. and L.L. Aylward.  2009.  Using biomonitoring equivalents to interpret human biomonitoring data in a public health risk context.  J. Appl. Toxicol. 29(4):275-288.

Kirman CR, Sweeney LM, Gargas ML, Kinzell JH.  2009.  Evaluation of possible modes of action for acute effects of methyl iodide in laboratory animals.  Inhal Toxicol.  21(6):537-51.

LaKind, J.S., S.M. Hays, L.L. Aylward, and D.Q. Naiman.  2009.  Perspective on serum dioxin levels in the United States: An evaluation of the NHANES data.  J. Exp. Sci. Environ. Epidemiol. 19:435-441.

Moore, J.M., J.L. Newsted, M. Hecker, M.J. Zwiernik, S.D. Fitzgerald, D.P. Kay, X. Zhang, E.G. Higley, L.L. Aylward, K.J. Beckett, R.A. Budinsky, S.J. Bursian, and J.P. Giesy.  2009.  Hepatic P450 enzyme activity, tissue morphology and histology of mink (Mustela vison) exposed to polychlorinated dibenzofurans (PCDFs).  Arch. Environ. Contam. Toxicol.  57:416–425.

Poet TS, Kirman CR, Gargas ML,  Hinderliter PD.  2009. Quantitative Risk Analysis for N-Methyl Pyrrolidone using Physiologically Based Pharmacokinetic and Benchmark Dose Modeling. (Submitted.

Sweeney LM, Kirman CR, Gannon SA, Thrall KD, Gargas ML, Kinzell JH. 2009. Development of a physiologically based pharmacokinetic (PBPK) model for methyl iodide in rats, rabbits, and humans.  Inhal Toxicol. 21(6):552-82.

Sweeney LM, Kirman CR, Gargas ML, Dugard PH.  2009.  Contribution of trichloroacetic acid to liver tumors observed in perchloroethylene (perc)-exposed mice.  Toxicology. 16;260(1-3):77-83.

Sweeney, L.M., Kirman, C.R., Albertini, R.J., Yan, Y., Clewell, H.J. III, Filser, J.G., Csanady, G., Pottenger, L.H., Banton, M.I., Graham, C.J., Andrews, L.S. II, Papciak, R.J. and Gargas, M.L. 2009. Derivation of inhalation toxicology reference values for propylene oxide using mode of action analysis: Example of a threshold carcinogen. Crit. Rev. Toxicol., accepted for publication.

Aylward, L.L., and S.M. Hays.  2008.  Biomonitoring equivalents (BE) dossier for 2,4-dichlorophenoxyacetic acid (2,4-D) (CAS No. 94-75-7).  Reg. Toxicol. Pharmacol. 51:S37-S48.

Aylward, L.L., Charnley, G., Goodman, J., and Rhomberg, L.  2008.  Comment on “Chronic Disease and Early Exposure to Air-Borne Mixtures. 2. Exposure Assessment.”  Environ. Sci. Technol.  42(6) 2201 – 2201.

Aylward, L.L., H.A. Barton, and S.M. Hays.  2008.  Biomonitoring equivalents (BE) dossier for toluene (CAS No. 108-88-3).  Reg. Toxicol. Pharmacol. 51:S27-S36.

Aylward, L.L., J.E. Goodman, G. Charnley, L.R. Rhomberg.  2008.  A margin of exposure approach to assessment of non-cancer risks of dioxins based on human exposure and response data.  Environ. Health Persp.  116:1344-1351.

Aylward, L.L., J.S. LaKind, and S.M. Hays.  2008.  Biomonitoring equivalents (BE) dossier for trihalomethanes.  Reg. Toxicol. Pharmacol. 51:S68-S77.

Aylward, L.L., J.S. LaKind, and S.M. Hays.  2008.  Derivation of Biomonitoring Equivalent (BE) values for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds:  A screening tool for interpretation of biomonitoring data in a risk assessment context.  J. Toxicol. Enivron. Health Pt. A. 71(22):1499-1508.

Buchanan, S., Pyatt, D.W. and Carpenter, J. 2008 "Successful Lyophilization and Ambient Temperature Storage of Human Umbilical Cord Blood" Accepted, Stem Cells.

Budinsky, R.A., J.C. Rowlands, S. Casteel, G. Fent, C.A. Cushing, J. Newsted, M.V.  Ruby, and L.L. Aylward.  2008.  A pilot study of oral bioavailability of dioxins and furans from contaminated soils:  Impact of differential hepatic enzyme activity and species differences.  Chemosphere 70:1774-1786.

Hays SM, Aylward LL, LaKind JS, Bartels MJ, Barton HA, Boogaard PJ, Brunk C, DiZio S, Dourson M, Goldstein DA, Kilpatrick ME, Krewski D, Krishnan, K, Lipscomb J, Nordberg M, Okino M, Tan Y-M, Viau C, Yager JW.  2008.  Guidelines for the derivation of Biomonitoring Equivalents:  Report from the Biomonitoring Equivalents Expert Workshop.  Reg. Toxicol. Pharmacol.  51:S4-S15.

Hays, S.M., and L.L. Aylward.  2008.  Biomonitoring equivalents (BE) dossier for acrylamide (AA) (CAS No. 79-06-1).  Reg. Toxicol. Pharmacol.  51:S57-S67.

Hays, S.M., L.L. Aylward, and J.S. Lakind.  2008.  Introduction to the Biomonitoring Equivalents Pilot Project: Development of guidelines for the derivation and communication of Biomonitoring Equivalents.  Reg. Toxicol. Pharmacol. 51:S1-S2.

Hays, S.M., M. Nordberg, J.W. Yager, and L.L. Aylward.  2008.  Biomonitoring equivalents (BE) dossier for cadmium (Cd) (CAS No. 7440-43-9). Reg. Toxicol. Pharmacol. 51:S49-S56.

Kirman CR, Sweeney LM, Gargas ML, Strother DE, Collins JJ, Deskin R.  2008.  Derivation of noncancer reference values for acrylonitrile.  Risk Anal. 28(5):1375-94.

LaKind, J.S., L. Barraj, N. Tran, and L.L. Aylward.  2008.  Environmental chemicals in people: Challenges in interpreting biomonitoring information.  J. Environ. Health. 70(9):61-64.

LaKind, J.S., L.L. Aylward, C. Brunk, S. DiZio, M. Dourson, D.A. Goldstein, M.E. Kilpatrick, D. Krewski, M.J. Bartels, H.A. Barton, P.J. Boogaard, J. Lipscomb, K. Krishnan, M. Nordberg, M. Okino, Y.-M. Tan, C. Viau, J.W. Yager, and S.M. Hays.  2008.  Guidelines for the communication of Biomonitoring Equivalents:  Report from the Biomonitoring Equivalents Expert Workshop.  Reg. Toxicol. Pharmacol.  51:S16-S26.

Pyatt, D.W., Natelson, E. and Golden, R. 2008 "Is Inhalation Exposure to Formaldehyde a Biologically Plausible Cause of Lymphohematopoietic Malignancies?"  Regulatory Toxicology and Pharmacology, V51, p119-133.

Simon, T., C.R. Kirman, L.L. Aylward, R.A. Budinsky, J.C. Rowlands, and T.F. Long.  2008.  Linear and non-linear estimates of cancer potency of 2,3,4,7,8-pentachlorodibenzofuran.  Toxicol. Sci. 106(2):519-37.

Zwiernik, M.J., J. Moore, J.-S. Khim, L.L. Williams, D.P. Kay, S. Bursian, L.L. Aylward, and J.P. Giesy.  2008.  Non-destructive scat sampling in exposure assessment of mink (Mustela vison) exposed to polychlorinated dibenzofurans (PCDFs).  Arch. Environ. Contam. Toxicol.  55(3):529-537.

Zwiernik, M.J., S. Bursian, L.L. Aylward, D. Kay, J. Moore, J. C. Rowlands, K. Woodburn, M. Shotwell, J.-S. Khim, J.P. Giesy, and R.A. Budinsky.  2008.  Toxicokinetics of  2,3,7,8-TCDF and 2,3,4,7,8-PeCDF in mink (Mustela vison) at ecologically relevant exposures.  Toxicol. Sci. 105:33-43.

Butterworth, B.E., L.L. Aylward, S.M. Hays.  2007.  A mechanism-based cancer risk assessment for 1,4-dichlorobenzene.  Regul. Toxicol. Pharmacol. 49:138-48.

Hays, S.M., R. Becker, H.-W. Leung, L.L. Aylward, and D.W. Pyatt.  2007.  Biomonitoring equivalents: A screening approach for interpreting biomonitoring results from a public health risk perspective. Regulatory Toxicology and Pharmacology.  47(1):96-109.

Lakind, J.S., Holgate, S.T., Ownby, D., Mansure, A., Helms, P., Pyatt, D.W. and Hays, S.M. 2007 "A critical review of the use of clara cell secretory protein [CC16] as a biomarker of acute of chronic pulmonary effects.  Biomarkers, 2007, p1-23.

Nichols, B.R., K.L. Hentz, L. Aylward, S.M. Hays, J.C. Lamb.  2007.  Age-specific reference ranges for polychlorinated biphenyls (PCB) based on the NHANES 2001-2002 survey.  J. Toxicol Environ Health A.  70:1873-7. 

Pyatt, D.W., L.L. Aylward, and S.M. Hays.  2007.  Is age an independent risk factor for chemically induced acute myelogenous leukemia in children?  J. Toxicol. Environ. Health B Crit. Rev. 10(5):379-400.

Sielken RL Jr, Valdez-Flores C, Gargas ML, Kirman CR, Teta MJ, Delzell E.  2007. Cancer risk assessment for 1,3-butadiene: dose-response modeling from an epidemiological perspective.  Chem Biol Interact.

Buchanan, S., Pyatt, D.W. and Carpenter, J. 2006 "Freeze-drying human hematopoietic stem and progenitor cells loaded with trehalose."  Accepted, Nature Biotechnology.

Cheng, H.,  L.L. Aylward, T.B. Starr, C. Beall, R. Brunet, G. Carrier, and E. Delzell. 2006.  TCDD exposure-response analysis and risk assessment.  Risk Analysis.  26(4):1059-71.

Connor, K.C. and L.L. Aylward.  2006. Human response to dioxin:  Aryl hydrocarbon receptor (AhR) molecular structure, function, and dose-response data for enzyme induction indicate an impaired human AhR. J. Toxicol. Environ. Health Part B:  Critical Reviews. 9:147-171.

Golden, B., Pyatt D.W. and Shields, P. 2006 "Formaldehyde as a potential human leukemogen: an assessment of biologic plausibility" Critical Reviews in Toxicology, V36:135-153.

Gray, M.N., L.L. Aylward, and R.E. Keenan. 2006.  Relative cancer potencies of selected dioxin-like compounds on a body burden basis:  Comparison to current Toxic Equivalency Factors (TEFs).  J. Toxicol. Environ. Health.  69:907-917

Guzelian, P., L. Quattrochi, N. Karch, L. Aylward, and R. Kaley.  2006.  Does dioxin exert toxic effects in humans at or near current background body levels?: An evidence-based conclusion.  Human and Experimental Toxicology.  25:99-105.

Hays, S.M. and Pyatt, D.W. 2006 Risk assessment for children exposed to decabromodiphenyl (Oxide) ether (Deca) in the United States." Integrated Environmental Assessment and Management, V2 (1):2-12.

Rowlands, J.C., R.A. Budinsky, L.L. Aylward, A.S. Faqi, and E.W. Carney.  2006.  Sex ratio of the offspring of Sprague-Dawley rats exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in utero and lactationally in a three-generation study.  Toxicol. Appl. Pharmacol.  216(1):29-33

Aylward, L., R. Brunet, T. Starr, G. Carrier, E. Delzell, H. Cheng, and C. Beall.  2005.  Exposure reconstruction for the TCDD-exposed NIOSH cohort using a concentration- and age-dependent model of elimination.  Risk Anal.  25(4):945-956.

Aylward, L.L., J.C. Lamb, and S. Lewis.  2005.  Issues in risk assessment for developmental effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds.  Toxicol. Sci. 87(1):3-10.

Aylward, L.L., R.C. Brunet, G. Carrier, S.M. Hays, C.A. Cushing, L.L. Needham, D.G. Patterson, Jr., P.M. Gerthoux, P. Brambilla, and P. Mocarelli.  2005.  Concentration-dependent TCDD elimination kinetics in humans:  Toxicokinetic modeling for moderately to highly exposed adults from Seveso, Italy, and Vienna, Austria, and impact on dose estimates for the NIOSH cohort.  J. Exp. Anal. Environ. Epidemiol. 15:51–65.

Buchanan, S., Menze, M., Hand, S., Pyatt, D.W. and Carpenter, J. 2005 "Cryopreservation of human hematopoietic stem and progenitor cells loaded with trehalose: Transient permeabilization via the ATP-Dependent P2Z receptor channel."  Cell Preservation Technology, V3(4):212-222.

Kirman, C.R., Gargas, M.L., Marsh, G.M., Strother, D.E., Klaunig, J.E., Collins, J.J., and Deskin, R. 2005. Cancer dose-response assessment for acrylonitrile based upon rodent brain tumor incidence: Use of epidemiologic, mechanistic, and pharmacokinetic support for nonlinearity. Reg. Toxicol. Pharmacol., 43, 85-103.

Kirman, C.R., Sweeney, L.M., Corley, R. and Gargas, M.L. 2005. Using physiologically-based pharmacokinetic modeling to address nonlinear kinetics and changes in rodent physiology and metabolism due to aging and adaptation in deriving reference values for propylene glycol methyl ether and propylene glycol methyl ether acetate. Risk Anal., 25(2), 271-284.

Pyatt, D.W., Hays, S. and Cushing, C.  2005 "Do children have increased susceptibility for developing secondary acute myelogenous leukemia?" Chemico-Biological Interactions, V153-154:223-229.

Wright, P.C., T. F. Long, and L. L. Aylward.  2005.  Twenty-five years of dioxin cancer risk assessment.  Natural Resources & Environment.  19(4):31-35.

Buchanan, S., Gross, S., Mehmet, T., Carpenter, J. and Pyatt, D. W. 2004 "A novel methodology for cell preservation using non-toxic sugars".  Journal of Stem Cells and Development, V13(3):295-305.

Gaylor, D.W. and L.L. Aylward.  2004.   An evaluation of benchmark dose methodology for non-cancer continuous-data health effects in animals due to exposures to dioxin (TCDD).  Reg. Toxicol. Pharmacol 40:9–17.

Kirman, C.R., Sweeney, L.M., Teta, M.J., Sielken, R.L., Valdez-Flora, C., Albertini, R. and Gargas, M.L. 2004. Addressing nonlinearity in the exposure-response relationship for a genotoxic carcinogen: Cancer potency estimates for ethylene oxide. Risk Anal., 24(5), 1165-1183.

Ruby, M.V., S.W. Casteel, T.J. Evans, K.A. Fehling, D.J. Paustenbach, B.D. Landenberger, R.A. Budinsky, J.P. Giesy, and L.L. Aylward.  2004.  Rapid communication:  Background concentrations of dioxins/furans in Sprague-Dawley rats and juvenile swine.  J. Toxicol. Environ. Health 67(11):845–850.

Sweeney, L.M., Kirman, C.R., Morgott, D.A. and Gargas, M.L. 2004. Estimation of interindividual variation in oxidative metabolism of dichloromethane in human volunteers. Toxicol Lett., 154(3), 201-216.

Zheng, T., Pyatt, D.W., Gross, S., Le, A. and Irons, R. D. 2004 "Hydroquinone modulates GM-CSF in TF.1 cells".  Leukemia, 18(7):1296-304.

Aylward, L., C. Kirman, D. Cher, S. Hays.  2003.  Re: analysis of dioxin cancer threshold.  Environ. Health Perspect. 111(10):A510.

Aylward, L.L., S.M. Hays, J.S. LaKind, and J.J. Ryan.  2003.  Rapid communication: partitioning of persistent lipophilic compounds, including dioxins, between human milk lipid and blood lipid: an initial assessment.  J Toxicol Environ Health A. 66(1):1–5.

Hays, S.M., and L.L. Aylward.  2003.  Dioxin risks in perspective:  past, present, and future. Regul Toxicol Pharmacol. 37(2):202–217.

Hays, Sean, M., Cushing, C., Leung, H-W., Pyatt, D., Holicky, K. and Paustenbach, D. 2003 "Exposure of infants and children in the U.S. to the flame retardant decabromodiphenyl oxide (DBDPO)". Journal of Children's Health, V1(4):449-475.

Kerzic, P., Pyatt, D.W., Zheng, T. and Irons, R.D. 2003 "Inhibition of NF-kappa B by hydroquinone, a benzene metabolite, sensitizes human bone marrow progenitor cells to TNF-  induced apoptosis". Toxicology,V187(2-3):127-137.

Kirman, C.R., Gargas, M.L., Deskin, R., Tonner-Navarro, L. and Andersen, M.E. 2003. A physiologically based pharmacokinetic model for acrylamide and its metabolite, glycidamide, in the rat. J. Toxicol. Environ. Health, 66(3), 253-274.

Kirman, C.R., Sweeney, LM, Meek ME, Gargas, ML. 2003. Assessing the dose dependency of allometric scaling performance using physiologically based pharmacokinetic modeling. Reg. Toxicol. Pharmacol., 38, 345-367.

Aylward, L.L. and S.M. Hays.  2002.  Temporal trends in human TCDD body burden:  Decreases over three decades and implications for exposure levels.  J. Exp. Anal. Environ. Epidemiol. 12:319–328.

Baker, R.K., Pyatt, D.W., Irons, R.D. and Kroll, D.J.  2001 "Benzene Metabolites Antagonize Etoposide Stabilized Cleavable Complexes of DNA-Topoisomerase- ".  Blood, V98:830-833.

Irons, R.D., Pyatt, D.W., Gross, S. A. and Stillman, W.S.  2001 "Hematopoietic stem and progenitor cells as targets for biologically reactive intermediates".  Advances in Experimental and Medical Biology, V500:441-9.

Irons, R.D., Pyatt, D.W., Yang, J., Zheng, T., Stillman, W.S., Le, A. and Gustaphson, D.2001 "Comparative toxicology of dithiocarbamates and butadiene metabolites in human lymphoid and bone marrow cells."  Chemical- Biological Interactions, V135-136:615-625.

Sweeney, L.M., Tyler, T.R., Kirman, C.R., Corley, R.A., Reitz, R.H., Paustenbach, D.J., Holson. J.F., Whorton, M.D., Thompson, K.M. and Gargas, M.L. 2001. Proposed occupational exposure limits for select ethylene glycol ethers using PBPK models and Monte Carlo simulations. Tox. Sci., 62 (1), 124-139.

Irons, R.D., Pyatt, D. W., Stillman, W. S., Som, D., Claffey, D. and Ruth, J.  2000  "Comparative toxicity of butadiene and it's putative metabolites in human CD34+ bone marrow cells. Toxicology, V150:99-106.

Kirman, C.R., Hays, S.M., Kedderis, G.L., Gargas, M.L., and Strother, D.E.  2000.  Improving cancer dose-response characterization using physiologically based pharmacokinetic modeling: an analysis of pooled data for acrylonitrile-induced brain tumors to assess cancer potency in the rat.  Risk Anal., 20(1), 135-151.

Pyatt, D.W., Mehos, B., Yang, J. and Irons, R.D. 2000 "Effects of the anti-rheumatic herbal medicine, Tripterygii, on CD34+ bone marrow cell function and survival."  Molecular Pharmacology, V57:1-7.

Pyatt, D.W., Stillman, W.S., Yang, J., Cano, L.L. and Irons, R.D. 2000 "Hydroquinone, an active metabolite of benzene, inhibits PMA-induced activation of NF- B in primary human CD19+ B lymphocytes." Cell Biology and Toxicology, V16 (1):41-51.

Pyatt, D.W., Yang, J, Stillman, W.S. and Irons, R.D. 2000 "Dithiocarbamates inhibit hematopoiesis via a copper dependent mechanism." Biochemical and Biophysical Research Communications, V274(2):513-518.

Pyatt, D.W., Stillman, W.S., Yang, J., Zheng, T., Gross, S. and Irons, R.D. 1999 "An essential role for NF- B in human CD34+ bone marrow cell survival."  Blood, V93 (10):1-8.

Arfsten, D.P., L.L. Aylward, N.J. and Karch.  1998.  Chromium.  In: Immunotoxicology of Environmental and Occupational Metals.  J.T. Zelikoff and P.T. Thomas, (eds.) Taylor and Francis, London.

Aylward, L.L., N.J. Karch, S.M. Hays, and D.J. Paustenbach.  1998.  Response to comment on a relative susceptibility of animals and humans to the cancer hazard posed by 2,3,7,8-Tetrachlorodibenzo-p-dioxin using internal measures of dose.  Environ. Sci. Technol. 32(4): 551–552.

Hays, S.M., Long, T.F., Kirman, C.R., and Gargas, M.L.  1998.  Potential uses of PBPK modeling to improve the regulation of exposure to toxic compounds.  Risk Policy Report, December 18, 1998, Guest Perspectives.

Pyatt, D.W., Stillman, W.S. and Irons, R.D. 1998 "Hydroquinone, a reactive metabolite of benzene, inhibits NF-? B in primary human CD4+ T lymphocytes."  Toxicology and Applied Pharmacology,V149:178-184.

Pyatt, D.W., Stillman, W.S. Gruntmeir, J. and Irons, R.D. 1998 "Dimethyldithiocarbamate (DMDTC) inhibits activation of human CD4+ T lymphocytes."  Toxicology, V128:83-90.

Thomas, P.T., L.L. Aylward, and N.J. Karch.  1998.  Immunotoxicity of dioxin:  Is the TEF concept premature?  In: Chlorine and Chlorine Compounds in the Paper Industry.  Victor Turoski, (ed.), Sleeping Bear Press, Chelsea, Michigan. pp. 307–314.

Gross, S., Helm, K., Gruntmeir, J., Pyatt, D.W., Stillman, W.S. and Irons, R.D. 1997 "Characterization and phenotypic analysis of differentiating CD34+ human bone marrow cells in liquid culture."  European Journal of Haematology, V.59:318-326.

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